Requirements
msc
5–10 years
fplc
molecular cloning
antibody engineering
cell culture
BEPC is seeking a highly motivated Scientist to join our client’s site in Pleasanton, CA. This role will support molecular cloning, cell culture, FPLC purification, and antibody engineering and characterization activities. The Scientist will join a team focused on monoclonal antibody development for IVD and CDx assays and will actively participate in antibody development, engineering, production, and characterization. The position requires the ability to evaluate, summarize, and report study results, make independent decisions, and collaborate with teams at multiple sites.
Note: This is a W2 only role — C2C, C2H will not be considered
- Knowledge of biophysical characterization techniques (DSC, DLS).
- Experience with advanced protein modification analysis and impact on function.
- Domain knowledge in oncology, immunology, or protein chemistry.
- Experience in antibody purification and characterization, including protein A/G–based purification (FPLC) and analytical methods such as ELISA, SDS-PAGE, WB, HPLC, and IHC.
- Experience and in-depth knowledge in monoclonal antibody development and antibody engineering.
- Experience with computational protein engineering and antibody epitope modeling.
- Familiarity with formulation and stability studies for final antibody products.
- Demonstrated experience with the end-to-end antibody development process, from molecular cloning through expression, purification, and biochemical/functional characterization.
- Experience: 5–10 years of relevant hands-on experience (most important).
- Advanced proficiency in molecular cloning techniques (PCR, restriction/ligation, Gibson assembly).
- Hands-on experience expressing antibodies in mammalian systems (HEK293, CHO).
- Is aware of new developments in the field and refers to possible diagnostic applications.
- Significant experience with transient protein expression in mammalian cell culture systems.
- Ability to interpret structural data (PDB files) and relate it to experimental outcomes.
- Familiarity with antibody sequences and sequence analysis software.
- Experience with laboratory automation and workflow optimization.
- Strong hands-on experience with antibody sequence analysis and antibody architecture (VH/VL, CDRs, frameworks).
- Education: MSc.
Benefits
Pay Rate: $63.00 - $66.50 /hour - Determined based on experience
BEPC Inc., founded in 2007, is a 100% employee-owned company providing top-tier consulting and staffing solutions across industries like technology, engineering, manufacturing, and project management. At BEPC, we are driven by innovation and a commitment to excellence. We take pride in fostering a collaborative and innovative environment where our team members thrive. With competitive benefits, including medical, dental, vision, and life insurance, BEPC is dedicated to supporting our employees' personal and professional growth.
Benefits include medical, dental, vision, and life insurance
Training + Development
Information not given or found