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Scientist II
Employer undisclosedRole managed by a recruiter
Develop LC/MS bioanalysis for biologics, support PK/TK/PD studies.
3d ago
$59 - $62
Expert & Leadership (13+ years), Experienced (8-12 years)
Contractor
South San Francisco, CA
Onsite
Role
What you would be doing
assay optimization
data analysis
affinity purification
lc/ms operation
bioanalysis development
data communication
- Facilitate assay optimization and implementation to ensure laboratory capacity and data quality.
- Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
- Perform affinity purification of therapeutic proteins (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-siRNA conjugates, and fusion proteins) from biological matrices.
- Operate and maintain LC/MS instruments to generate high-quality experimental data.
- The main function of this position is to develop and implement LC/MS (liquid chromatography/mass spectrometry)-based bioanalysis and in vitro characterization assays for novel biologics entities.
- Communicate data interpretation internally and externally.
What you bring
liquid handling
mass spectrometry
oligonucleotide
chemistry degree
lc/ms
pk/pd
- Hands-on experience with automated liquid handling systems is highly desired.
- Hands-on experience with QQQ (SCIEX), qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is highly desired.
- Hands-on experience with oligonucleotide analysis is highly desired.
- Degree in chemistry, pharmacology or other related fields. BS with 5+ years or MS with 2+ years in a pharmaceutical industry setting with a focus on mass spectrometry.
- Experience on routine LC/MS-based bioanalysis to support in vivo PK, TK, and PK/PD studies
- Prior industry experience in drug discovery/development is preferred. In-depth understanding of PK, TK and PK/PD studies and corresponding bioanalytical assays as well as in vitro characterization assays is highly desired.
- Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor.
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